RCAN1 抗体 (AA 201-250)
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北京 101111
Quick Overview for RCAN1 抗体 (AA 201-250) (ABIN1451085)
抗原
See all RCAN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-250
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原理
- DSCR 1 Antibody
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特异性
- DSCR 1 Polyclonal Antibody detects endogenous levels of DSCR 1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human RCAN1. AA range:201-250
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
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别名
- RCAN1
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背景
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Synonyms: RCAN1, ADAPT78, CSP1, DSC1, DSCR1, Calcipressin-1, Adapt78, Down syndrome critical region protein 1, Myocyte-enriched calcineurin-interacting protein 1, MCIP1, Regulator of calcineurin 1
Background: The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013],
Gene Name: RCAN1
Protein Name: Calcipressin-1
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分子量
- 22 kDa
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基因ID
- 1827
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OMIM
- 602917
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UniProt
- P53805
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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