Atrophin 1 抗体 (AA 81-130)
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Quick Overview for Atrophin 1 抗体 (AA 81-130) (ABIN1451055)
抗原
See all Atrophin 1 (ATN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 81-130
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原理
- Atrophin-1 Antibody
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特异性
- Atrophin-1 Polyclonal Antibody detects endogenous levels of Atrophin-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human ATN1. AA range:81-130
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Atrophin 1 (ATN1)
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别名
- ATN1
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背景
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Synonyms: ATN1, D12S755E, DRPLA, Atrophin-1, Dentatorubral-pallidoluysian atrophy protein
Background: Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein. [provided by RefSeq, Jul 2016],
Gene Name: ATN1
Protein Name: Atrophin-1
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分子量
- 124 kDa
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基因ID
- 1822
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OMIM
- 125370
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UniProt
- P54259
抗原
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