Acetylcholinesterase 抗体 (AA 551-600)
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Quick Overview for Acetylcholinesterase 抗体 (AA 551-600) (ABIN1451010)
抗原
See all Acetylcholinesterase (AChE) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 551-600
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原理
- AChE Antibody
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特异性
- AChE Polyclonal Antibody detects endogenous levels of AChE protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human ACHE. AA range:551-600
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Acetylcholinesterase (AChE)
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别名
- ACHE
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背景
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Synonyms: ACHE, Acetylcholinesterase, AChE
Background: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively
Gene Name: ACHE
Protein Name: Acetylcholinesterase
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分子量
- 67 kDa
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基因ID
- 43
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OMIM
- 100740
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UniProt
- P22303
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途径
- Skeletal Muscle Fiber Development
抗原
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