IL17RA 抗体 (AA 141-190)
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北京 101111
Quick Overview for IL17RA 抗体 (AA 141-190) (ABIN1450932)
抗原
See all IL17RA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 141-190
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原理
- IL-17Rα Antibody
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特异性
- IL-17Rα Polyclonal Antibody detects endogenous levels of IL-17Rα protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human IL17RA. AA range:141-190
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- IL17RA (Interleukin 17 Receptor A (IL17RA))
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别名
- IL17RA
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背景
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Synonyms: IL17RA, IL17R, Interleukin-17 receptor A, IL-17 receptor A, IL-17RA, CDw217, CD antigen CD217
Background: Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor, IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014],
Gene Name: IL17RA
Protein Name: Interleukin-17 receptor A
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分子量
- 96 kDa
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基因ID
- 23765
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OMIM
- 605461
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UniProt
- Q96F46
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途径
- SARS-CoV-2 Protein Interactome
抗原
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