GTF3C4 抗体 (AA 611-660)
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北京 101111
Quick Overview for GTF3C4 抗体 (AA 611-660) (ABIN1450890)
抗原
See all GTF3C4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 611-660
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原理
- TFIIIC90 Antibody
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特异性
- TFIIIC90 Polyclonal Antibody detects endogenous levels of TFIIIC90 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human TF3C4. AA range:611-660
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GTF3C4 (General Transcription Factor IIIC, Polypeptide 4 (GTF3C4))
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背景
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Synonyms: GTF3C4, General transcription factor 3C polypeptide 4, TF3C-delta, Transcription factor IIIC 90 kDa subunit, TFIIIC 90 kDa subunit, TFIIIC90, Transcription factor IIIC subunit delta
Background: catalytic activity:Acetyl-CoA + histone = CoA + acetylhistone.,function:Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the TFIIIC subunit 4 family.,subunit:Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6. Interacts with BRF1, GTF3C1, GTF3C2, GTF3C5, GTF3C6, POLR3C and POLR3F.,
Gene Name: GTF3C4
Protein Name: General transcription factor 3C polypeptide 4
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分子量
- 92 kDa
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基因ID
- 9329
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OMIM
- 604892
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UniProt
- Q9UKN8
抗原
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