DOK5 抗体 (AA 101-150)
Our Local Distributor
北京 101111
Quick Overview for DOK5 抗体 (AA 101-150) (ABIN1450881)
抗原
See all DOK5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 101-150
-
原理
- Dok-5 Antibody
-
特异性
- Dok-5 Polyclonal Antibody detects endogenous levels of Dok-5 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- The antiserum was produced against synthesized peptide derived from human DOK5. AA range:101-150
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- DOK5 (Docking Protein 5 (DOK5))
-
别名
- DOK5
-
背景
-
Synonyms: DOK5, C20orf180, Docking protein 5, Downstream of tyrosine kinase 5, Insulin receptor substrate 6, IRS-6, IRS6
Background: docking protein 5(DOK5) Homo sapiens The protein encoded byThis gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2014],
Gene Name: DOK5
Protein Name: Docking protein 5
-
分子量
- 35 kDa
-
基因ID
- 55816
-
OMIM
- 608334
-
UniProt
- Q9P104
抗原
-