TSG101 抗体 (AA 281-330)
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北京 101111
Quick Overview for TSG101 抗体 (AA 281-330) (ABIN1450872)
抗原
See all TSG101 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 281-330
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原理
- Tsg 101 Antibody
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特异性
- Tsg 101 Polyclonal Antibody detects endogenous levels of Tsg 101 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human TSG101. AA range:281-330
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
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别名
- TS101
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背景
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Synonyms: TSG101, Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101
Background: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008],
Gene Name: TSG101
Protein Name: Tumor susceptibility gene 101 protein
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分子量
- 43 kDa
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基因ID
- 7251
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OMIM
- 601387
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UniProt
- Q99816
抗原
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