PINX1 抗体 (AA 121-170)
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北京 101111
Quick Overview for PINX1 抗体 (AA 121-170) (ABIN1450857)
抗原
See all PINX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 121-170
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原理
- PinX1 Antibody
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特异性
- PinX1 Polyclonal Antibody detects endogenous levels of PinX1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PINX1. AA range:121-170
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
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别名
- PINX1
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背景
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Synonyms: PINX1, LPTL, LPTS, PIN2/TERF1-interacting telomerase inhibitor 1, Liver-related putative tumor suppressor, Pin2-interacting protein X1, Protein 67-11-3, TRF1-interacting protein 1
Background: domain:The TID (telomerase inhibiting domain) domain is sufficient to bind TERT and inhibit its activity.,function:Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.,similarity:Belongs to the PINX1 family.,similarity:Contains 1 G-patch domain.,subcellular location:In nucleoli and at telomere speckles.,subunit:Binds to MCRS1, TERT and TERF1.,tissue specificity:Ubiquitous, expressed at low levels. Not detectable in a number of hepatocarcinoma cell lines.,
Gene Name: PINX1
Protein Name: PIN2/TERF1-interacting telomerase inhibitor 1
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分子量
- 37 kDa
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基因ID
- 54984
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OMIM
- 606505
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UniProt
- Q96BK5
抗原
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