MDS1 抗体 (AA 1-50)
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北京 101111
Quick Overview for MDS1 抗体 (AA 1-50) (ABIN1450839)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50
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原理
- PRDM3 Antibody
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特异性
- PRDM3 Polyclonal Antibody detects endogenous levels of PRDM3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human MECOM. AA range:1-50
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亚型
- IgG
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anti-Myelodysplasia Syndrome 1 (MDS1) (Internal Region) antibody
MDS1 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MDS1 (Myelodysplasia Syndrome 1 (MDS1))
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别名
- Myelodysplasia Syndrome 1
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背景
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Synonyms: MECOM, MDS1, MDS1 and EVI1 complex locus protein MDS1, Myelodysplasia syndrome 1 protein, Myelodysplasia syndrome-associated protein 1
Background: The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011],
Gene Name: MECOM
Protein Name: MDS1 and EVI1 complex locus protein MDS1
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分子量
- 18 kDa
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基因ID
- 4197
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OMIM
- 600049
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UniProt
- Q13465
抗原
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