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PDX1 抗体 (AA 27-76)

The 兔 多克隆 anti-PDX1 antibody (ABIN1450734) specifically detects PDX1 in WB 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1450734
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for PDX1 抗体 (AA 27-76) (ABIN1450734)

抗原

See all PDX1 抗体
PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

适用

  • 143
  • 51
  • 31
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 157
  • 9
  • 2
兔

克隆类型

  • 140
  • 28
多克隆

标记

  • 73
  • 13
  • 8
  • 7
  • 7
  • 7
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PDX1 antibody is un-conjugated

应用范围

  • 118
  • 73
  • 42
  • 37
  • 27
  • 25
  • 16
  • 15
  • 14
  • 13
  • 4
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 15
    • 13
    • 13
    • 9
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 27-76

    原理

    PDX-1 Antibody

    特异性

    PDX-1 Polyclonal Antibody detects endogenous levels of PDX-1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human PDX1. AA range:27-76

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

    别名

    PDX1

    背景

    Synonyms: PDX1, IPF1, Pancreas/duodenum homeobox protein 1, PDX-1, Glucose-sensitive factor, GSF, Insulin promoter factor 1, IPF-1, Insulin upstream factor 1, IUF-1, Islet/duodenum homeobox-1, IDX-1, Somatostatin-transactivating factor 1, STF-1

    Background: The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Jul 2008],

    Gene Name: PDX1

    Protein Name: Pancreas/duodenum homeobox protein 1

    分子量

    30 kDa

    基因ID

    3651

    OMIM

    125853

    UniProt

    P52945

    途径

    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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