JDP2 抗体 (AA 114-163)
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北京 101111
Quick Overview for JDP2 抗体 (AA 114-163) (ABIN1450713)
抗原
See all JDP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 114-163
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原理
- JDP2 Antibody
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特异性
- JDP2 Polyclonal Antibody detects endogenous levels of JDP2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human JDP2. AA range:114-163
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- JDP2 (Jun Dimerization Protein 2 (JDP2))
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别名
- JDP-2
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背景
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Synonyms: JDP2, Jun dimerization protein 2
Background: function:Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.,PTM:Phosphorylation of Thr-148 by MAPK8 in response to different stress conditions such as, UV irradiation, oxidatives stress and anisomycin treatments.,similarity:Belongs to the bZIP family. ATF subfamily.,similarity:Contains 1 bZIP domain.,subunit:Forms homodimer or heterodimer with JUN, JUNB, JUND, CEBPG and ATF2 thereby inhibiting transactivation by JUN, ATF2 and CEBPG (By similarity). Binds multiple DNA elements such as cAMP-response element (CRE) and TPA response element (TRE) either as homodimer or heterodimer.,
Gene Name: JDP2
Protein Name: Jun dimerization protein 2
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分子量
- 18 kDa
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基因ID
- 122953
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OMIM
- 608657
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UniProt
- Q8WYK2
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途径
- Chromatin Binding
抗原
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