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JDP2 抗体 (AA 114-163)

The 兔 多克隆 anti-JDP2 antibody (ABIN1450713) specifically detects JDP2 in WB 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1450713
发货至: 中国
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Quick Overview for JDP2 抗体 (AA 114-163) (ABIN1450713)

抗原

See all JDP2 抗体
JDP2 (Jun Dimerization Protein 2 (JDP2))

适用

  • 44
  • 12
  • 10
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 42
  • 2
兔

克隆类型

  • 41
  • 3
多克隆

标记

  • 20
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This JDP2 antibody is un-conjugated

应用范围

  • 38
  • 20
  • 13
  • 13
  • 10
  • 3
  • 3
  • 2
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 12
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 114-163

    原理

    JDP2 Antibody

    特异性

    JDP2 Polyclonal Antibody detects endogenous levels of JDP2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human JDP2. AA range:114-163

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    JDP2 (Jun Dimerization Protein 2 (JDP2))

    别名

    JDP-2

    背景

    Synonyms: JDP2, Jun dimerization protein 2

    Background: function:Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.,PTM:Phosphorylation of Thr-148 by MAPK8 in response to different stress conditions such as, UV irradiation, oxidatives stress and anisomycin treatments.,similarity:Belongs to the bZIP family. ATF subfamily.,similarity:Contains 1 bZIP domain.,subunit:Forms homodimer or heterodimer with JUN, JUNB, JUND, CEBPG and ATF2 thereby inhibiting transactivation by JUN, ATF2 and CEBPG (By similarity). Binds multiple DNA elements such as cAMP-response element (CRE) and TPA response element (TRE) either as homodimer or heterodimer.,

    Gene Name: JDP2

    Protein Name: Jun dimerization protein 2

    分子量

    18 kDa

    基因ID

    122953

    OMIM

    608657

    UniProt

    Q8WYK2

    途径

    Chromatin Binding
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