Huntingtin 抗体 (AA 387-436)
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北京 101111
Quick Overview for Huntingtin 抗体 (AA 387-436) (ABIN1450584)
抗原
See all Huntingtin (HTT) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 387-436
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原理
- Huntingtin Antibody
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特异性
- Huntingtin Polyclonal Antibody detects endogenous levels of Huntingtin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human Huntingtin. AA range:387-436
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亚型
- IgG
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anti-Huntingtin (HTT) antibody
HTT 适用: 人 IHC, WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Huntingtin (HTT) antibodyKD Validated HTT 适用: 人 WB, ICC, IF (p), FACS 宿主: 兔 Monoclonal 23GB6285 unconjugated Recombinant Antibody
anti-Huntingtin (HTT) (AA 81-190) antibodyHTT 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F1 unconjugated
anti-Huntingtin (HTT) (AA 85-200) antibodyHTT 适用: 人, 小鼠, 大鼠, 兔, 猴, 马, 犬, 绵羊, Pig, Hamster, 豚鼠, 山羊, 驴, Cow, 小鸡, Cat, Avian WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Huntingtin (HTT) (AA 81-190) antibodyHTT 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-Huntingtin (HTT) (AA 81-190) antibodyHTT 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Huntingtin (HTT) (AA 2703-2911) antibodyHTT 适用: 人, 兔 IHC, WB, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal unconjugated
anti-Huntingtin (HTT) (AA 81-191) antibodyHTT 适用: 人 IHC, WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F1 unconjugated
anti-Huntingtin (HTT) antibodyHTT 适用: 人 IHC, ELISA 宿主: 兔 Monoclonal 6F2 unconjugated Recombinant Antibody
anti-Huntingtin (HTT) (AA 782-920) antibodyHTT 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Huntingtin (HTT)
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别名
- Huntingtin
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背景
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Synonyms: HTT; HD; IT15; Huntingtin; Huntington disease protein; HD protein
Background: huntingtin(HTT) Homo sapiens Huntingtin is a disease gene linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product. A fairly broad range of trinucleotide repeats (9-35) has been identified in normal controls, and repeat numbers in excess of 40 have been described as pathological. The huntingtin locus is large, spanning 180 kb and consisting of 67 exons. The huntingtin gene is widely expressed and is required for normal development. It is expressed as 2 alternatively polyadenylated forms displaying different relative abundance in various fetal and adult tissues. The larger transcript is approximately 13.7 kb and is expressed predominantly in adult and fetal brain whereas the smaller transcript of approximately 10.3 kb is more widel
Gene Name: HTT
Protein Name: Huntingtin
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分子量
- 347 kDa
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基因ID
- 3064
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OMIM
- 143100
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UniProt
- P42858
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途径
- PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
抗原
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