SRF 抗体 (pThr159)
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北京 101111
Quick Overview for SRF 抗体 (pThr159) (ABIN1450509)
抗原
See all SRF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 126-175, pThr159
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原理
- SRF (phospho Thr159) Antibody
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特异性
- Phospho-SRF (T159) Polyclonal Antibody detects endogenous levels of SRF protein only when phosphorylated at T159.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human SRF around the phosphorylation site of Thr159. AA range:126-175
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- SRF (Serum Response Factor (SRF))
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别名
- SRF
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背景
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Synonyms: SRF, Serum response factor, SRF
Background: This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways, for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014],
Gene Name: SRF
Protein Name: Serum response factor
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分子量
- 51 kDa
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基因ID
- 6722
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OMIM
- 600589
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UniProt
- P11831
抗原
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