PKD2 抗体 (pSer812)
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北京 101111
Quick Overview for PKD2 抗体 (pSer812) (ABIN1450365)
抗原
See all PKD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 778-827, pSer812
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原理
- PKD2 (phospho Ser812) Antibody
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特异性
- Phospho-PKD2 (S812) Polyclonal Antibody detects endogenous levels of PKD2S812.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human PKD2 around the phosphorylation site of Ser812. AA range:778-827
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
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别名
- PKD2
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背景
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Synonyms: PKD2, Polycystin-2, Autosomal dominant polycystic kidney disease type II protein, Polycystic kidney disease 2 protein, Polycystwin, R48321
Background: polycystin 2, transient receptor potential cation channel(PKD2) Homo sapiens This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011],
Gene Name: PKD2
Protein Name: Polycystin-2
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分子量
- 96 kDa
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基因ID
- 5311
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OMIM
- 173900
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UniProt
- Q13563
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途径
- cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
抗原
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