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MAX 抗体 (pSer2)

The 兔 多克隆 anti-MAX antibody (ABIN1450344) specifically detects MAX in ELISA, IHC 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1450344
发货至: 中国
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Quick Overview for MAX 抗体 (pSer2) (ABIN1450344)

抗原

See all MAX 抗体
MAX (MYC Associated Factor X (MAX))

适用

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人, 小鼠, 大鼠

宿主

  • 87
  • 4
  • 2
兔

克隆类型

  • 88
  • 5
多克隆

标记

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This MAX antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 15
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    AA 1-50, pSer2

    原理

    Max (phospho Ser2) Antibody

    特异性

    Phospho-Max (S2) Polyclonal Antibody detects endogenous levels of Max protein only when phosphorylated at S2.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human MAX around the phosphorylation site of Ser2. AA range:1-50

    亚型

    IgG
  • 应用备注

    IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    MAX (MYC Associated Factor X (MAX))

    别名

    MAX

    背景

    Synonyms: MAX, BHLHD4, Protein max, Class D basic helix-loop-helix protein 4, bHLHd4, Myc-associated factor X

    Background: The protein encoded byThis gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],

    Gene Name: MAX

    Protein Name: Protein max

    分子量

    18 kDa

    基因ID

    4149

    OMIM

    154950

    UniProt

    P61244

    途径

    Mitotic G1-G1/S Phases
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