GFRA2 抗体
(1 reference)Quick Overview for GFRA2 抗体 (ABIN1450225)
抗原
See all GFRA2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Glial cell line-derived neurotrophic factor (GDNF) andneurturin (NTN) are two structurally related, potent neurotrophic factors thatplay key roles in the control of neuron survival and differentiation. GFRa-2 isa member of the GDNF receptor family. It is a glycosylphosphatidyl-inositol(GPI)-linkedcell surface receptor for both GDNF and NTN, and mediates activation of the RETtyrosine kinase receptor. This encoded protein acts preferentially as areceptor for NRTN compared to its other family member, GDNF family receptoralpha 1. http://www.ncbi.nlm.nih.gov/gene/2675
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产品特性
- Mono- and polyclonal antibodies to human growth factors and neural growth factor receptors.
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纯化方法
- GFRa-2 affinity purified
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亚型
- IgY
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anti-GDNF Family Receptor alpha 2 (GFRA2) (AA 301-360) antibody
GFRA2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 2 (GFRA2) (AA 242-415) antibodyGFRA2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 2 (GFRA2) (AA 117-314) antibodyGFRA2 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 2 (GFRA2) (C-Term) antibodyGFRA2 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, Cow, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 2 (GFRA2) (AA 377-391) antibodyGFRA2 适用: 人, 小鼠, 大鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 2 (GFRA2) (C-Term) antibodyGFRA2 适用: 人, 小鼠, 大鼠 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 2 (GFRA2) (AA 362-411) antibodyGFRA2 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 2 (GFRA2) (AA 360-464) antibodyGFRA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 2 (GFRA2) (AA 117-314) antibodyGFRA2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 2 (GFRA2) (Middle Region) antibodyGFRA2 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western immunoblotting, recommended dilution 1:5 000to 1:10 000, ELISA: 1:128 000 to 160 000, IF 1:500 to1:1000. Polyclonal antibody working titer has to beestablished practically for each particular antigen and assay format
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说明
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Synonym: GDNF receptor beta, Neurturin receptor alpha, RETligand 2TGF-beta-related neurotrophic factor receptor 2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/ml
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缓冲液
- Concentrated ammonium sulphate in PBS pH 7.4
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注意事项
- As product is (NH4)2SO4 precipitate, mix well by pipetting or vortexing prior use
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储存条件
- 4 °C
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储存方法
- This product is shipped in non-frozen liquid form in ambient conditions
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: "Return of the Tbx5; lineage-tracing reveals ventricular cardiomyocyte-like precursors in the injured adult mammalian heart." in: NPJ Regenerative medicine, Vol. 8, Issue 1, pp. 13, (2023) (PubMed).
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: "Return of the Tbx5; lineage-tracing reveals ventricular cardiomyocyte-like precursors in the injured adult mammalian heart." in: NPJ Regenerative medicine, Vol. 8, Issue 1, pp. 13, (2023) (PubMed).
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- GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
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别名
- GFRa-2
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背景
- Recombinant His-tagged human GFRα-2 protein producedusing CHO-based cell line. For production of hGFRα-2, glycosylphosphatidyl-inositol GPI-anchor was removedand protein was secreted to the cell culture supernatant. Protein was purifiedby Ni-affinity chromatography following gel-filtration from cell culturesupernatant
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UniProt
- O00451
抗原
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