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Aggrecan 抗体

ACAN 适用: 人, Cow WB, IP, IHC (p), IHC (fro), EIA 宿主: 小鼠 Monoclonal HAG7D4 (7D4) unconjugated
产品编号 ABIN1450192
发货至: 中国
  • 抗原 See all Aggrecan (ACAN) 抗体
    Aggrecan (ACAN)
    适用
    • 66
    • 55
    • 40
    • 31
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, Cow
    宿主
    • 80
    • 17
    • 1
    小鼠
    克隆类型
    • 73
    • 25
    单克隆
    标记
    • 46
    • 15
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Aggrecan antibody is un-conjugated
    应用范围
    • 70
    • 40
    • 26
    • 26
    • 26
    • 19
    • 15
    • 12
    • 8
    • 7
    • 4
    • 4
    • 2
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human and Bovine.
    纯化方法
    Prepared by Affinity Chromatography on Protein G from Tissue Culture Supernatant
    免疫原
    Purified Human articular cartilage Aggrecan. Remarks: Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
    克隆位点
    HAG7D4 (7D4)
    亚型
    IgG1
    Top Product
    Discover our top product ACAN Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the lyophilized product at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.
  • Anders, Mollenhauer, Beberhold, Kinne, Venbrocks: "Gelatin-based haemostyptic Spongostan as a possible three-dimensional scaffold for a chondrocyte matrix?: an experimental study with bovine chondrocytes." in: The Journal of bone and joint surgery. British volume, Vol. 91, Issue 3, pp. 409-16, (2009) (PubMed).

  • 抗原
    Aggrecan (ACAN)
    别名
    Aggrecan (ACAN 产品)
    别名
    AGC1 antibody, AGCAN antibody, CSPG1 antibody, CSPGCP antibody, MSK16 antibody, SEDK antibody, Agc antibody, Agc1 antibody, Cspg1 antibody, b2b183Clo antibody, cmd antibody, aggrecan antibody, aggrecan core protein antibody, ACAN antibody, Acan antibody, LOC100380783 antibody, AGC antibody
    背景
    Aggrecan is a member of a family of large, aggregating proteoglycans (also including versican, brevican and neurocan) which is found in articular cartilage. Aggrecan is composed of three major domains: G1, G2, and G3. Between the G1 and G2 domains there is an interglobulin region (IGD). The IGD region is the major site of cleavage by specific proteases like metalloproteinases (MMPs) and aggrecanase. Aggrecan cleavage has been associated with a number of degenerative diseases including rheumatoid arthritis and osteoarthritis. There is evidence that this family of proteoglycans modulates cell adhesion, migration, and axonal outgrowth in the CNS.Synonyms: ACAN, AGC1, CSPG1, Cartilage-specific proteoglycan core protein, Chondroitin sulfate proteoglycan core protein 1, MSK16
    基因ID
    176, 9606
    UniProt
    P16112
    途径
    Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
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