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PHOX2B 抗体 (Middle Region)

This anti-PHOX2B antibody is a 兔 多克隆 antibody detecting PHOX2B in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1450171
发货至: 中国

Quick Overview for PHOX2B 抗体 (Middle Region) (ABIN1450171)

抗原

See all PHOX2B 抗体
PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 27
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多克隆

标记

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This PHOX2B antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Middle Region

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    15 amino acid synthetic peptide near the center of Human PHOX2B

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

    别名

    PHOX2B

    背景

    PHOX2A and PHOX2B (Paired mesoderm homeobox protein) are closely related, paired-homeodomain transcription factors that function as determinants of the noradrenergic phenotype during embryogenesis. PHOX2 proteins are crucial for the regulation of endogenous hydroxylases in neural crest cells and promote sympathetic neuron generation. Human PHOX2B contains one DNA binding homeobox domain and is required for the differentiation of all central and nonperipheral noradrenergic centers in the brain. In contrast, PHOX2A controls only the differentiation of the main noradrenergic center of the brain. Regulation of PHOX2 may have therapeutic utility in aging or disorders involving degeneration of noradrenergic neurons .Synonyms: NBPhox, Neuroblastoma Phox, PHOX2B homeodomain protein, PMX2B, Paired mesoderm homeobox protein 2B, Paired-like homeobox 2B

    基因ID

    8929

    NCBI登录号

    NP_003915
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