LZTS2 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for LZTS2 抗体 (C-Term) (ABIN1450155)
抗原
See all LZTS2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- A 17 amino acid synthetic peptide near the carboxy terminus of Human LZTS2
-
亚型
- IgG
-
-
anti-Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2) (AA 470-669) antibody
LZTS2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2) antibodyLZTS2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2) (AA 1-669) antibodyLZTS2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2) (AA 71-120) antibodyLZTS2 适用: 人, 小鼠, 大鼠, Cow, 犬, 山羊, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- LZTS2 (Leucine Zipper, Putative Tumor Suppressor 2 (LZTS2))
-
别名
- LZTS2
-
背景
- The leucine zipper putative tumor suppressor 2 (LZTS2, also known as LAPSER1), a member of the LZTS family, is a negative regulator of the Wnt signaling pathway. It represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. LZTS2 is involved in cytokinesis and regulates katanin-mediated microtubule severing and release from the centrosome. LZTS2 may negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. LZTS2 is highly expressed in testis and prostate, but it is deleted in multiple cancers, including prostate tumors, suggesting that LZTS2 acts as a potential tumor suppressor.Synonyms: KIAA1813, LAPSER1, LZTS2, Leucine zipper putative tumor suppressor 2, hLZTS2
-
基因ID
- 84445
-
NCBI登录号
- NP_115805
抗原
-
