Nicalin 抗体 (C-Term)
Quick Overview for Nicalin 抗体 (C-Term) (ABIN1450143)
抗原
See all Nicalin (NCLN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Multiple isoforms of NCLN are known to exist.
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 18 amino acid synthetic peptide near the carboxy terminus of Human NCLN
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亚型
- IgG
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anti-Nicalin (NCLN) (AA 44-144) antibody
NCLN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Nicalin (NCLN) (N-Term) antibodyNCLN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nicalin (NCLN) (AA 214-522) antibodyNCLN 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: 1-2 μg/ml.
Positive Control: Mouse heart tissue lysate.
Immunofluorescence: Start at 2.5 μg/ml.
Immunohistochemistry on Paraffin Sections: Start at 2.5 μg/ml.
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Nicalin (NCLN)
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别名
- Nicalin
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背景
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Nicalin, along with its binding partner Nomo, is a novel signaling antagonist to Nodals, signaling factors of the TGF-beta superfamily that play a key role in vertebrate development. Nicalin is distantly related to Nicastrin, a component of the Alzheimer’s disease-associated gamma-secretase, and is thought to have a similar function. Another protein, TMEM147, has also been recently identified as associating with Nicalin and NOMO as part of the gamma-secretase-like complex.
Synonyms: NCLN -
基因ID
- 56926
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NCBI登录号
- NP_064555
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UniProt
- Q969V3
抗原
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