SIGLEC15 抗体 (N-Term)
The 兔 多克隆 anti-SIGLEC15 antibody (ABIN1450134) specifically detects SIGLEC15 in WB 和 IHC (p).
The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1450134
发货至:
中国
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Quick Overview for SIGLEC15 抗体 (N-Term) (ABIN1450134)
抗原
See all SIGLEC15 抗体
SIGLEC15
(Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This SIGLEC15 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- N-Term
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交叉反应 （详细）
- Species reactivity (expected):Human, Mouse, Rat.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 15 amino acid synthetic peptide near the amino terminus of Human SIGLEC15
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亚型
- IgG
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anti-Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (AA 274-302), (C-Term) antibody
SIGLEC15 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB29353 unconjugated
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应用备注
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WB: 1 - 2 ug/mL, IHC: 2.5 ug/mL
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))
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别名
- SIGLEC15 / CD33L3
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背景
- Siglecs are vertebrate cell-surface lectins that recognize sialylated glycans and are involved in many physiological processes, such as glycoprotein turnover, cellular trafficking, and pathogen recognition. Most Siglecs are expressed on cells of the immune system. SIGLEC15 is a type-I transmembrane protein consisting of two immunoglobulin (Ig)-like domains, a transmembrane domain containing a lysine residue, and a short cytoplasmic tail. SIGLEC15 can interact with the activating adaptor molecules DAP12/10. Its activating signaling potential and unique preference for glycan recognition implies that SIGLEC15 may be involved in the immune surveillance of tumors and probably plays a conserved, regulatory role in the immune system of vertebrates.Synonyms: CD33 antigen-like 3, SIGLEC-15, Sialic acid-binding Ig-like lectin 15
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基因ID
- 284266
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NCBI登录号
- NP_998767
抗原
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