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SIGLEC15 抗体 (N-Term)

SIGLEC15 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1450134
发货至: 中国
  • 抗原 See all SIGLEC15 抗体
    SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))
    抗原表位
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 24
    • 3
    • 1
    克隆类型
    • 24
    • 4
    多克隆
    标记
    • 13
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIGLEC15 antibody is un-conjugated
    应用范围
    • 16
    • 13
    • 10
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应 (详细)
    Species reactivity (expected):Human, Mouse, Rat.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    15 amino acid synthetic peptide near the amino terminus of Human SIGLEC15
    亚型
    IgG
    Top Product
    Discover our top product SIGLEC15 Primary Antibody
  • 应用备注
    WB: 1 - 2 ug/mL, IHC: 2.5 ug/mL
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))
    别名
    SIGLEC15 / CD33L3 (SIGLEC15 产品)
    背景
    Siglecs are vertebrate cell-surface lectins that recognize sialylated glycans and are involved in many physiological processes, such as glycoprotein turnover, cellular trafficking, and pathogen recognition. Most Siglecs are expressed on cells of the immune system. SIGLEC15 is a type-I transmembrane protein consisting of two immunoglobulin (Ig)-like domains, a transmembrane domain containing a lysine residue, and a short cytoplasmic tail. SIGLEC15 can interact with the activating adaptor molecules DAP12/10. Its activating signaling potential and unique preference for glycan recognition implies that SIGLEC15 may be involved in the immune surveillance of tumors and probably plays a conserved, regulatory role in the immune system of vertebrates.Synonyms: CD33 antigen-like 3, SIGLEC-15, Sialic acid-binding Ig-like lectin 15
    基因ID
    284266
    NCBI登录号
    NP_998767
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