FOXRED2 抗体 (N-Term)
This anti-FOXRED2 antibody is a 兔 多克隆 antibody detecting FOXRED2 in WB, IF 和 EIA. Suitable for 人.
产品编号 ABIN1450133
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for FOXRED2 抗体 (N-Term) (ABIN1450133)
抗原
See all FOXRED2 抗体
FOXRED2
(FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))
适用
人
宿主
兔
克隆类型
多克隆
标记
This FOXRED2 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
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抗原表位
- N-Term
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 17 amino acid synthetic peptide near the amino terminus of Human FOXRED2
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亚型
- IgG
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anti-FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2) antibody
FOXRED2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2) (AA 501-684) antibodyFOXRED2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FOXRED2 (FAD-Dependent Oxidoreductase Domain Containing 2 (FOXRED2))
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别名
- FOXRED2
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背景
- FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER associated degradation (ERAD). It has been proposed to bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Upon knockdown of FOXRED2, the degradation of the ERAD model substrate ribophorin 332 is delayed, and the overall level of polyubiquitinated cellular proteins is decreased. Defects in the related protein FOXRED1 are a cause of mitochondrial complex I deficiency (MT-C1D), suggesting the FOXRED2 may also play a role in MT-C1D.Synonyms: FAD-dependent oxidoreductase domain-containing protein 2
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基因ID
- 80020
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途径
- SARS-CoV-2 Protein Interactome
抗原
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