TSHZ3 抗体 (N-Term)
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Quick Overview for TSHZ3 抗体 (N-Term) (ABIN1450132)
抗原
See all TSHZ3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse, Rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 18 amino acid synthetic peptide near the amino terminus of human TSHZ3 / ZNF537
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TSHZ3 (Teashirt Zinc Finger Homeobox 3 (TSHZ3))
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别名
- TSHZ3 / ZNF537
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背景
- The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. In mice, the known three TSHZ proteins are expressed in distinct patterns in the developing and adult brain, suggesting that they play a role in the establishment of regional identity and specification of cell types within the brain. Both TSHZ3 and TSHZ1 have been found to interact with FE65, an adapter protein that binds to the amyloid protein precursor (APP) in neurons. Together with SET, a component of the inhibitor of acetyl transferase, and histone deacetylases, these proteins formed a gene-silencing complex whose target includes caspase-4. Recent experiments have also suggested this family of proteins may be involved in carcinogenesis.Synonyms: KIAA1474, TSH3, Teashirt homolog 3, Zinc finger protein 537
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基因ID
- 57616
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NCBI登录号
- NP_065907
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途径
- Regulation of Muscle Cell Differentiation
抗原
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