C9ORF116 抗体 (N-Term)
This 兔 多克隆 anti-C9ORF116 antibody specifically detects C9ORF116 in WB, EIA 和 IF. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN1450123
发货至:
中国
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中国
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北京 101111
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Quick Overview for C9ORF116 抗体 (N-Term) (ABIN1450123)
抗原
C9ORF116
(Chromosome 9 Open Reading Frame 116 (C9ORF116))
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
This C9ORF116 antibody is un-conjugated
应用范围
Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF)
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抗原表位
- N-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 16 amino acid synthetic peptide near the amino terminus of Human PIERCE1
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亚型
- IgG
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anti-Chromosome 9 Open Reading Frame 116 (C9ORF116) (N-Term) antibody
C9ORF116 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 9 Open Reading Frame 116 (C9ORF116) (AA 39-88) antibodyC9ORF116 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- C9ORF116 (Chromosome 9 Open Reading Frame 116 (C9ORF116))
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别名
- C9orf116
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背景
- PIERCE1, also known as C9orf116, is an important p53 target gene contributing to normal DNA damage response and may play crucial roles in maintaining genomic integrity against genotoxic stresses, including UVC irradiation (1,2). PIERCE1 exists as two alternatively spliced isoforms and is predominantly expressed in human small cell lung cancer (3-4). PIERCE1 knockdown induces down-regulation of proapoptotic genes including Ei24, Apaf1 and PTEN, suggesting that PIERCE1 is a proapoptotic gene. It is helpful for in-depth understanding of p53 pathways and the design of new cancer therapies (1-3).Synonyms: Pierce1, p53-induced expression in RB-null cells protein 1
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基因ID
- 138162
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NCBI登录号
- NP_001041730
抗原
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