SIVA1 抗体 (N-Term)
Quick Overview for SIVA1 抗体 (N-Term) (ABIN1450104)
抗原
See all SIVA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 16 amino acid synthetic peptide near the amino terminus of human SIVA
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anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-175) antibody
SIVA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-110) antibodySIVA1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (Internal Region) antibodySIVA1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-110) antibodySIVA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-175) antibodySIVA1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) antibodySIVA1 适用: 人 WB 宿主: 小鼠 Monoclonal 1G8 unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) antibodySIVA1 适用: 人 WB 宿主: 小鼠 Monoclonal 1C9 unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-110) antibodySIVA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))
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别名
- SIVA1 / SIVA
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背景
- SIVA plays an important role in the apoptotic pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. SIVA is a small cysteine-rich protein with a unique N-terminal amphipathic helical region, a death domain homology region (DDHR) and a C-terminal cysteine-rich B-box-like or zinc-finger-like structure. The DDHR domain binds to CD27 and induces apoptosis in T cells through a caspase-dependent mitochondrial pathway. SIVA inhibits BCL2L1 isoform Bcl-xL anti-apoptotic activity and inhibits activation of NFk-B and promotes T-cell receptor-mediated apoptosis. SIVA represents a potential therapeutic target for the treatment of neuronal cell death diseases.Synonyms: Apoptosis regulatory protein Siva, CD27-binding protein, CD27BP
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基因ID
- 10572
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NCBI登录号
- NP_068355
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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