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AFAP 抗体 (N-Term)

AFAP1 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1450096
发货至: 中国
  • 抗原 See all AFAP (AFAP1) 抗体
    AFAP (AFAP1) (Actin Filament Associated Protein 1 (AFAP1))
    抗原表位
    • 15
    • 8
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 44
    • 22
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 40
    • 4
    • 1
    克隆类型
    • 42
    • 3
    多克隆
    标记
    • 21
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AFAP antibody is un-conjugated
    应用范围
    • 42
    • 18
    • 13
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    AFAP1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of Human AFAP1
    亚型
    IgG
    Top Product
    Discover our top product AFAP1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    AFAP (AFAP1) (Actin Filament Associated Protein 1 (AFAP1))
    别名
    AFAP1 (AFAP1 产品)
    别名
    afap antibody, afap-110 antibody, AFAP antibody, AFAP-110 antibody, AFAP110 antibody, 2600003E23Rik antibody, 9630044L16Rik antibody, AI848729 antibody, Afap antibody, mKIAA3018 antibody, actin filament associated protein 1 antibody, AFAP1 antibody, afap1 antibody, Afap1 antibody
    背景
    The actin filament-associated protein AFAP1 (AFAP-110) is an actin cross-linking protein first identified as a substrate of the viral oncogene v-Src. AFAP1 has a fundamental role in actin cytoskeleton arrangement. It contains a carboxyterminal actin-binding domain that directly binds to F-actin and serves as an adaptor protein in the regulation of SRC and PKC signal transduction by several functional domains, including 2 pleckstrin homology (PH) domains, a Src homology 3-binding (SH3-binding) motif, and several SH2-binding motifs. It is overexpressed in prostate carcinoma and contributes to tumor growth by regulating cell-matrix adhesions and migration in the cancer cells. AFAP1 represent a possible therapeutic target for controlling tumorigenesis and metastasis.Synonyms: 110 kDa actin filament-associated protein, AFAP-110, Actin filament-associated protein 1
    基因ID
    60312
    NCBI登录号
    NP_940997
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