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PIWIL2 抗体 (Middle Region)

This anti-PIWIL2 antibody is a 兔 多克隆 antibody detecting PIWIL2 in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN1450077
发货至: 中国

Quick Overview for PIWIL2 抗体 (Middle Region) (ABIN1450077)

抗原

See all PIWIL2 抗体
PIWIL2 (Piwi-Like 2 (PIWIL2))

适用

  • 18
  • 10
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 19
  • 3
  • 1

克隆类型

  • 21
  • 2
多克隆

标记

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  • 1
  • 1
  • 1
  • 1
  • 1
This PIWIL2 antibody is un-conjugated

应用范围

  • 20
  • 12
  • 5
  • 2
  • 2
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  • 2
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    17 amino acid synthetic peptide near the center of Human PIWI-L2

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PIWIL2 (Piwi-Like 2 (PIWIL2))

    别名

    PIWIL2

    背景

    PIWI-L2 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. PIWI-L2 has been implicated in multiple roles including stem cell self-renewal and is highly expressed in many breast cancers. In these tumors, PIWI-L2 silences the expression of STAT3, a regulator of Bcl-XL and cyclin D1, allowing the proliferation and survival of breast cancer stem cells. Recent studies have shown that overexpression of PIWI-like proteins are potential biomarkers for colon and other cancers.Synonyms: CT80, Cancer/testis antigen 80, HILI, Hiwi-like, Mili, Miwi-like, PIWIL1L, Piwi-like protein 2

    基因ID

    55124

    NCBI登录号

    NP_00129193

    途径

    Stem Cell Maintenance
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