DRAXIN 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for DRAXIN 抗体 (C-Term) (ABIN1450058)
抗原
See all DRAXIN 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
交叉反应 (详细)
- Species reactivity (tested):Human, Mouse, Rat.
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- 17 amino acid synthetic peptide near the carboxy terminus of Human Neucrin
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))
-
别名
- Draxin
-
背景
- Neucrin, also known as Draxin, is a repulsive guidance protein for the spinal cord and forebrain commissures. It is thought to act as an antagonist of canonical Wnt signaling by inhibiting the stabilization of cytosolic beta-catenin. Ectopically expressed neucrin inhibited growth or caused misrouting of chick spinal cord commissural axons in vivo while Neucrin-null mice showed defasciculation of spinal cord commissural axons and an absence of all forebrain commisures. Other experiments in mice have shown that olfactory bulb axonal outgrowth is inhibited by Neucrin, suggesting that Neucrin functions as an inhibitory guidance cue for olfactory bulb axons.Synonyms: C1orf187, Dorsal repulsive axon guidance protein, Neucrin, PSEC0258
-
基因ID
- 374946
抗原
-