EI24 抗体 (C-Term)
This anti-EI24 antibody is a 兔 多克隆 antibody detecting EI24 in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for EI24 抗体 (C-Term) (ABIN1450056)
抗原
See all EI24 抗体
EI24
(Etoposide Induced 2.4 (EI24))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This EI24 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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抗原表位
- C-Term
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 19 amino acid synthetic peptide near the carboxy terminus of Human EI24
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亚型
- IgG
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anti-Etoposide Induced 2.4 (EI24) (AA 27-61) antibody
EI24 适用: 小鼠 WB 宿主: 兔 Polyclonal RB54173 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- EI24 (Etoposide Induced 2.4 (EI24))
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别名
- EI24
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背景
- The etoposide-induced 24 (EI24) protein is an immediate-early induction target of p53-mediated apoptosis and functions as a tumor suppressor. EI24 contains six transmembrane domains and is localized to the endoplasmic reticulum (ER). It binds to Bcl-2 and may contribute to apoptosis by modulating the activity and function of Bcl-2. EI24 is highly mutated in aggressive breast cancers and its loss in breast cancer tissue correlates with tumor invasiveness. Similar findings in invasive cervical carcinoma suggest that EI24 may be a promising therapeutic target in the treatment of invasive cancer.Synonyms: Etoposide-induced protein 2.4 homolog, PIG8, p53-induced gene 8 protein
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基因ID
- 9538
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NCBI登录号
- NP_004870
抗原
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