DPAGT1 抗体 (N-Term)
Quick Overview for DPAGT1 抗体 (N-Term) (ABIN1450055)
抗原
See all DPAGT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 17 amino acid synthetic peptide near the amino terminus of Human DPAGT1
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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The role of Alg13 N-acetylglucosaminyl transferase in the expression of pathogenic features of Candida albicans." in: Biochimica et biophysica acta. General subjects, Vol. 1861, Issue 4, pp. 789-801, (2017) (PubMed).
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The role of Alg13 N-acetylglucosaminyl transferase in the expression of pathogenic features of Candida albicans." in: Biochimica et biophysica acta. General subjects, Vol. 1861, Issue 4, pp. 789-801, (2017) (PubMed).
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- DPAGT1 (Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) (DPAGT1))
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别名
- DPAGT1
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背景
- The UDP-N-acetylglucosamine-dolichyl-phosphate N-acetyl-glucosaminephosphotransferase (DPAGT1) is an enzyme that catalyzes the first step in the dolichol-linked oligosaccharide pathway for glycoprotein biosynthesis. Mutations in this integral endoplasmic reticulum (ER) membrane protein enzyme belongs to the glycosyltransferase family 4 results in the congenital disorder of glycosylation type Ij with symptoms such as severe hypotonia, medically intractable seizures, mental retardation, microcephaly, and exotropia. Recent experiments have shown that DPAGT1 is a target of the Wnt/beta-catenin signaling pathway, with Wnt3a inducing higher DPAGT1 mRNA expression.Synonyms: DPAGT2, G1PT, GPT, GlcNAc-1-P transferase, N-acetylglucosamine-1-phosphate transferase, UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase
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基因ID
- 1798
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NCBI登录号
- NP_001373
抗原
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