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TMEM59L 抗体 (C-Term)

This 兔 多克隆 anti-TMEM59L antibody specifically detects TMEM59L in WB, IF, IHC (p) 和 EIA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1450042
发货至: 中国
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Quick Overview for TMEM59L 抗体 (C-Term) (ABIN1450042)

抗原

See all TMEM59L 抗体
TMEM59L (Transmembrane Protein 59-Like (TMEM59L))

适用

人, 小鼠, 大鼠

宿主

  • 25

克隆类型

  • 25
多克隆

标记

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This TMEM59L antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
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    C-Term

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse, Rat.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    19 amino acid synthetic peptide near carboxy terminus of Human TMEM59L

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    TMEM59L (Transmembrane Protein 59-Like (TMEM59L))

    别名

    TMEM59L

    背景

    Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59L is a type I membrane glycoprotein that is expressed in the brain. A related protein, TMEM59, is a Golgi-localized protein that modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP and inhibits APP transport and shedding.Synonyms: BSMAP, Brain-specific membrane-anchored protein, C19orf4, Transmembrane protein 59-like

    基因ID

    25789

    NCBI登录号

    NP_036241
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