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- 抗原 See all Pellino 1 (PELI1) 抗体
- Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Pellino 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- A 15 amino acid peptide near the carboxy terminus of Human Pellino 1
- 亚型
- IgG
- Top Product
- Discover our top product PELI1 Primary Antibody
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anti-Pellino E3 Ubiquitin Protein Ligase 1 (PELI1) (AA 1-250) antibody
PELI1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pellino E3 Ubiquitin Protein Ligase 1 (PELI1) (C-Term) antibodyPELI1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pellino E3 Ubiquitin Protein Ligase 1 (PELI1) (AA 107-156) antibodyPELI1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Pellino E3 Ubiquitin Protein Ligase 1 (PELI1) (AA 17-242) antibodyPELI1 适用: 人, Cow WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))
- 别名
- PELI1 (PELI1 产品)
- 背景
- The Pellino proteins are a highly homologous family of E3 ubiquitin ligases that act as upstream mediators in Toll-like receptor (TLR) pathways that lead to activation of MAP kinases and transcription factors. Pellino 1 is required for interleukin-1-mediated signaling through its interaction with the IRAK4-IRAK-TRAF6 complex, ultimately resulting in the activation of NF-kB. Like other members of the Pellino family, Pellino 1 is an E3 ubiquitin ligase, able to catalyze the polyubiquitination of IRAK1. It is activated via phosphorylation by either IRAK1 and IRAK4 or the IKK-related kinases IKK-epsilon and TBK1. In addition to phosphorylation, Pellino 1 activity is also modulated via ubiquitination and sumoylation.Synonyms: PRISM, Pellino 1, Pellino-1, Pellino-related intracellular-signaling molecule, Protein pellino homolog 1
- 分子量
- 46 kDa
- 基因ID
- 57162
- NCBI登录号
- NP_065702
- 途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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