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BIRC6 抗体 (C-Term)

This anti-BIRC6 antibody is a 兔 多克隆 antibody detecting BIRC6 in IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN1450019
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BIRC6 抗体 (C-Term) (ABIN1450019)

抗原

See all BIRC6 抗体
BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

适用

  • 24
  • 3
  • 1

宿主

  • 22
  • 2

克隆类型

  • 24
多克隆

标记

  • 12
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BIRC6 antibody is un-conjugated

应用范围

  • 12
  • 12
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    A 17 amino acid synthetic peptide near the carboxy terminus of Human BIRC6

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))

    别名

    BIRC6

    背景

    Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. BRUCE, also known as BIRC6, is an IAP family member protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. BRUCE regulates p53 and the mitochondrial pathway of apoptosis by facilitating the degradation of apoptotic proteins such as Caspase-9 and SMAC by ubiquitination.Synonyms: Apollon, Baculoviral IAP repeat-containing protein 6, KIAA1289, Ubiquitin-conjugating BIR domain enzyme apollon

    分子量

    534 kDa

    基因ID

    57448

    NCBI登录号

    NP_057336
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