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FAM193B 抗体 (N-Term)

This anti-FAM193B antibody is a 兔 多克隆 antibody detecting FAM193B in WB, IF 和 EIA. Suitable for 人.
产品编号 ABIN1450012
发货至: 中国

Quick Overview for FAM193B 抗体 (N-Term) (ABIN1450012)

抗原

FAM193B (Family with Sequence Similarity 193, Member B (FAM193B))

适用

宿主

  • 2

克隆类型

  • 2
多克隆

标记

  • 2
This FAM193B antibody is un-conjugated

应用范围

  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 2
    • 1
    N-Term

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    16 amino acid synthetic peptide near the amino terminus of Human FAM193B

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    FAM193B (Family with Sequence Similarity 193, Member B (FAM193B))

    别名

    FAM193B

    背景

    FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans.Synonyms: Family with sequence similarity 193 member B, IRIZIO

    分子量

    99 kDa

    基因ID

    54540

    UniProt

    Q96PV7
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