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- 抗原 See all CENPW 抗体
- CENPW (Centromere Protein W (CENPW))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CENPW antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 16 amino acid synthetic peptide near the amino terminus of Human CENPW
- 亚型
- IgG
- Top Product
- Discover our top product CENPW Primary Antibody
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anti-Centromere Protein W (CENPW) (N-Term) antibody
CENPW 适用: 人 WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- CENPW (Centromere Protein W (CENPW))
- 别名
- CENP-W (CENPW 产品)
- 别名
- C6orf173 antibody, CUG2 antibody, 2610036L11Rik antibody, Cug2 antibody, CENP-W antibody, centromere protein W antibody, CENPW antibody, Cenpw antibody
- 背景
- CENPW was initially identified as a gene that was upregulated in multiple cancers, and whose overexpression in mouse fibroblast cells gave rise to distinct cancer-specific phenotypes. It was later found to be a nuclear protein that associated with CENPT, a component of CENPA nucleosome complex in the centromere, and is required for proper kinetochore function. CENPW also specifically interacts with the nucleolar phosphoprotein nucleophosmin, also known as B23 It has been suggested that nucleophosmin functions in the assembly of the kinetochore by interacting with CENPW during interphase. Overexpression of CENPW in the SKOV-3 human ovarian cancer cell line as well as in the zebrafish embryo led to apoptosis, suggesting that high levels of CENPW induces apoptotic cell death.Synonyms: C6orf173, CENPW, CUG2, Cancer-up-regulated gene 2 protein, Centromere protein W
- 基因ID
- 387103
- NCBI登录号
- NP_001012525
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