DDX60 抗体 (Middle Region)
This anti-DDX60 antibody is a 兔 多克隆 antibody detecting DDX60 in WB, IF 和 EIA. Suitable for 人, 小鼠 和 大鼠.
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Quick Overview for DDX60 抗体 (Middle Region) (ABIN1450010)
抗原
See all DDX60 抗体
DDX60
(DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 60 (DDX60))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This DDX60 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
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抗原表位
- Middle Region
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 17 amino acid synthetic peptide near the center of Human DDX60
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亚型
- IgG
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anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 60 (DDX60) (AA 1-183) antibody
DDX60 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A10 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DDX60 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 60 (DDX60))
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别名
- DDX60
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背景
- DDX60 is a DEXD/H Box RNA helicase and the human homolog of the S. cerevisiae Ski2, a cofactor of RNA exosome. Expression of DDX60 increases after viral infection and binds to endogenous RIG-I, a cytoplasmic viral RNA sensor, as well as other RIG-I-like receptors such as MDA5 and LGP2. These proteins activate TBK1 and IKK-e, signaling IRF3 and NF-kB-responsive genes in the innate immune response pathway. DDX60 is required for the RIG-I- or MDA5-dependent response to viral infection, but is dispensable for TLR3-mediated signaling.Synonyms: FLJ20035, Probable ATP-dependent RNA helicase DDX60
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分子量
- 188 kDa
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基因ID
- 55601
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NCBI登录号
- NP_060101
抗原
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