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Selenoprotein K 抗体 (C-Term)

This anti-Selenoprotein K antibody is a 兔 多克隆 antibody detecting Selenoprotein K in WB, IF 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1450003
发货至: 中国

Quick Overview for Selenoprotein K 抗体 (C-Term) (ABIN1450003)

抗原

See all Selenoprotein K (SELK) 抗体
Selenoprotein K (SELK)

适用

人, 小鼠, 大鼠

宿主

  • 10
  • 1

克隆类型

  • 11
多克隆

标记

  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
This Selenoprotein K antibody is un-conjugated

应用范围

  • 11
  • 9
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    SELK antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of Human SELK

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Selenoprotein K (SELK)

    背景

    SELK is a selenoprotein, containing a selenocysteine residue at its active site. SELK is localized to the endoplasmic reticulum and is highly expressed in the heart, where it may function as an antioxidant. SELK can bind to proteins such as the ER-associated degradation (ERAD) components p97 ATPase, Derlin-1 and -2, and SelS as well as proteins in the oligosaccharyltransferase complex, suggesting that SELK may be involved in the Derlin-dependent ERAD of glycosylated misfolded proteins. SELK is also thought to be important in Ca2+ flux in immune cells, and is cleaved by m-calpain in resting macrophages. When these macrophages are activated through different Toll-like receptors, this cleavage is inhibited

    分子量

    10 kDa

    基因ID

    58515

    NCBI登录号

    NP_067060
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