NDFIP1 抗体 (N-Term)
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北京 101111
Quick Overview for NDFIP1 抗体 (N-Term) (ABIN1450002)
抗原
See all NDFIP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- A 19 amino acid synthetic peptide near the amino terminus of Human NDFIP1
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亚型
- IgG
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anti-Nedd4 Family Interacting Protein 1 (NDFIP1) (AA 2-116) antibody
NDFIP1 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 1 (NDFIP1) (C-Term) antibodyNDFIP1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 1 (NDFIP1) (C-Term) antibodyNDFIP1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 1 (NDFIP1) (AA 1-221) antibodyNDFIP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 1 (NDFIP1) (AA 1-116) antibodyNDFIP1 适用: 人 EIA, RIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- NDFIP1 (Nedd4 Family Interacting Protein 1 (NDFIP1))
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别名
- NDFIP1
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背景
- The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.Synonyms: N4WBP5, NEDD4 family-interacting protein 1, PSEC0192, PSEC0223
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分子量
- 24 kDa
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基因ID
- 80762
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NCBI登录号
- NP_085048
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途径
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Negative Regulation of Transporter Activity
抗原
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