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BCL6 抗体 (Middle Region)

The 兔 多克隆 anti-BCL6 antibody (ABIN1449999) specifically detects BCL6 in WB 和 EIA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1449999
发货至: 中国
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Quick Overview for BCL6 抗体 (Middle Region) (ABIN1449999)

抗原

See all BCL6 抗体
BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

适用

  • 166
  • 57
  • 25
  • 9
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 102
  • 64
  • 1

克隆类型

  • 105
  • 62
多克隆

标记

  • 80
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This BCL6 antibody is un-conjugated

应用范围

  • 80
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  • 31
  • 27
  • 17
  • 11
  • 11
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 61
    • 12
    • 11
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    BCL6 antibody was raised against an 18 amino acid synthetic peptide near the center of Human BCL6

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

    别名

    Bcl-6

    背景

    BCL6 was first identified as a proto-oncogene in diffuse large B cell lymphoma. BCL6, a transcriptional repressor, plays an important role in lymphomagenesis. It binds Stat recognition-like DNA elements and is required for affinity maturation of mature B cells in germinal centers and Th1/Th2 differentiation, a process that critically depends on BCL6-mediated transcriptional repression of p53. BCL6 is a pharmacological target for eradication of leukemia-initiating cells in chronic myeloid leukemia (CML).Synonyms: B-cell lymphoma 6 protein, BCL-5, BCL5, BCL6, LAZ-3, LAZ3, ZBTB27, ZNF51, Zinc finger and BTB domain-containing protein 27, Zinc finger protein 51

    分子量

    78 kDa

    基因ID

    604

    NCBI登录号

    NP_001124317

    途径

    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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