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RGS22 抗体 (N-Term)

RGS22 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1449995
发货至: 中国
  • 抗原 See all RGS22 抗体
    RGS22 (Regulator of G-Protein Signaling 22 (RGS22))
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    N-Term
    适用
    • 30
    • 8
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 30
    克隆类型
    • 30
    多克隆
    标记
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RGS22 antibody is un-conjugated
    应用范围
    • 20
    • 19
    • 15
    • 11
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    A 19 amino acid synthetic peptide near the amino terminus of Human RGS22
    亚型
    IgG
    Top Product
    Discover our top product RGS22 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    RGS22 (Regulator of G-Protein Signaling 22 (RGS22))
    别名
    RGS22 (RGS22 产品)
    别名
    PRTD-NY2 antibody, RGD1565493 antibody, regulator of G protein signaling 22 antibody, regulator of G-protein signaling 22 antibody, regulator of G-protein signalling 22 antibody, RGS22 antibody, Rgs22 antibody
    背景
    Regulator of G-protein signaling (RGS) proteins contain an 120 amino acid conserved domain, termed the RGS domain, that acts as a GTPase-activating protein that acts to reduce the signal transmitted by the receptor-activated G-alpha subunit (1,2). RGS22 is a recently identified member of this family that localizes to the testis and can interact with guanine nucleotide binding proteins alpha 11, 12, and 13 (GNA11, GNA12, and GNA13). While RGS22 has been postulated to play a role in spermiogenesis in the testis, it is also expressed in several cancer cell lines with an epithelial origin and associated with cancer metastasis. Its overexpression in a highly metastatic cancer causes a decrease in cell migration and a reduction of the invasive potential of the cells, suggesting that RGS22 may be a potential prognostic biomarker for metastasis.Synonyms: Regulator of G-protein signaling 22
    分子量
    139 kDa
    基因ID
    26166
    NCBI登录号
    NP_056483
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling
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