RGS22 抗体 (N-Term)
Quick Overview for RGS22 抗体 (N-Term) (ABIN1449995)
抗原
See all RGS22 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- A 19 amino acid synthetic peptide near the amino terminus of Human RGS22
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亚型
- IgG
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anti-Regulator of G-Protein Signaling 22 (RGS22) antibody
RGS22 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 22 (RGS22) (N-Term) antibodyRGS22 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 22 (RGS22) (Internal Region) antibodyRGS22 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 22 (RGS22) (AA 216-265) antibodyRGS22 适用: 人, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of G-Protein Signaling 22 (RGS22) (N-Term) antibodyRGS22 适用: 人, 大鼠, Cow, Pig, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- RGS22 (Regulator of G-Protein Signaling 22 (RGS22))
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别名
- RGS22
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背景
- Regulator of G-protein signaling (RGS) proteins contain an 120 amino acid conserved domain, termed the RGS domain, that acts as a GTPase-activating protein that acts to reduce the signal transmitted by the receptor-activated G-alpha subunit (1,2). RGS22 is a recently identified member of this family that localizes to the testis and can interact with guanine nucleotide binding proteins alpha 11, 12, and 13 (GNA11, GNA12, and GNA13). While RGS22 has been postulated to play a role in spermiogenesis in the testis, it is also expressed in several cancer cell lines with an epithelial origin and associated with cancer metastasis. Its overexpression in a highly metastatic cancer causes a decrease in cell migration and a reduction of the invasive potential of the cells, suggesting that RGS22 may be a potential prognostic biomarker for metastasis.Synonyms: Regulator of G-protein signaling 22
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分子量
- 139 kDa
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基因ID
- 26166
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NCBI登录号
- NP_056483
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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