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CBX4 抗体 (N-Term)

The 兔 多克隆 anti-CBX4 antibody is suitable to detect CBX4 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IF 和 EIA.
产品编号 ABIN1449992
发货至: 中国
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Quick Overview for CBX4 抗体 (N-Term) (ABIN1449992)

抗原

See all CBX4 抗体
CBX4 (Chromobox Homolog 4 (CBX4))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CBX4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    A 17 amino acid synthetic peptide near the amino terminus of Human CBX4

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CBX4 (Chromobox Homolog 4 (CBX4))

    别名

    CBX4 / PC2

    背景

    Polycomb group (PcG) proteins are chromatin-associated proteins which are important for embryonic and adult stem cell self-renewal and maintenance. At least two distinct human PcG complexes have been identified. Polycomb repressive complex I (PRC1) contains CBX4/Pc2, HPH1 and RING domain-containing proteins (RING1, RING2 and BMI1). CBX4 (Chromobox protein homolog 4 or PC2), which functions as a transcriptional suppressor, is a candidate of KyoT2-binding proteins. It is a E3 SUMO-protein ligase which facilitates SUMO1 conjugation. Depletion of CBX4 results in decreased cellular resistance to ionizing radiation. CBX4 is directly involved in the cellular response to DNA damage.Synonyms: Chromobox protein homolog 4, E3 SUMO-protein ligase CBX4, Polycomb 2 homolog

    分子量

    62 kDa

    基因ID

    8535

    NCBI登录号

    NP_003646
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