Myc Target 1 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for Myc Target 1 抗体 (C-Term) (ABIN1449981)
抗原
See all Myc Target 1 (MYCT1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
交叉反应 (详细)
- Species reactivity (tested):Human, Mouse, Rat.
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- 17 amino acid synthetic peptide near the carboxy terminus of Human MYCT1
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- Myc Target 1 (MYCT1)
-
别名
- MYCT1
-
背景
- MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.Synonyms: MTLC, MTMC1, Myc target protein 1
-
分子量
- 26 kDa
-
基因ID
- 80177
-
NCBI登录号
- NP_079383
抗原
-