SGSM1 抗体 (Middle Region)
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北京 101111
Quick Overview for SGSM1 抗体 (Middle Region) (ABIN1449980)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- SGSM1 antibody was raised against a 17 amino acid synthetic peptide near the center of human SGSM1.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- SGSM1 (Small G Protein Signaling Modulator 1 (SGSM1))
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别名
- SGSM1
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背景
- Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM1 (RUTBC2) is a 1,148 amino acid protein that localizes to the Golgi apparatus and is mainly expressed in the CNS. SGSM1 interacts with RAP and RAB subfamily members of the small G proteins, and function as modulators of RAP and RAB-mediated neuronal signal transduction and vesicular transportation pathways.Synonyms: RUTBC2, Small G protein signaling modulator 1
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分子量
- 126 kDa
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基因ID
- 129049
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NCBI登录号
- NP_001035037
抗原
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