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PLA1A 抗体 (C-Term)

This anti-PLA1A antibody is a 兔 多克隆 antibody detecting PLA1A in WB, IF 和 EIA. Suitable for 人 和 大鼠.
产品编号 ABIN1449969
发货至: 中国

Quick Overview for PLA1A 抗体 (C-Term) (ABIN1449969)

抗原

See all PLA1A 抗体
PLA1A (Phospholipase A1 Member A (PLA1A))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This PLA1A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    交叉反应 (详细)

    Species reactivity (tested):Human, Rat.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    17 amino acid synthetic peptide near the carboxy terminus of Human PLA1A

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PLA1A (Phospholipase A1 Member A (PLA1A))

    别名

    PLA1A

    背景

    PLA1A is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine (PS) in liposomes and can also hydrolyze PS in apoptotic cells and activate platelets where the resulting 2-acyl-lysophosphatidylserine acts as a lipid mediator for mast cells, T cells, and neural cells, suggesting that a major function of PLA1A may be the production of lysophospholipid mediators. PLA1A is upregulated in rat peripheral blood cells bearing long-term surviving cardiac allograft. PLA1A is also expressed in human THP-1-derived macrophages and this expression is upregulated in cells treated with lipopolysaccharide, a TLR4 ligand. This upregulation is inhibited with corticosteroids, which are often used at high dosages to suppress chronic allograft rejection.Synonyms: NMD, PSPLA1, Phospholipase A1 member A

    分子量

    50 kDa

    基因ID

    51365

    NCBI登录号

    NP_056984
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