CMPK2 抗体 (C-Term)
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Quick Overview for CMPK2 抗体 (C-Term) (ABIN1449968)
抗原
See all CMPK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse, Rat.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 19 amino acid synthetic peptide near the carboxy terminus of Human CMPK2
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CMPK2 (Cytidine Monophosphate (UMP-CMP) Kinase 2, Mitochondrial (CMPK2))
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别名
- CMPK2
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背景
- UMP-CMP kinase 2 (CMPK2) is the first nucleoside monophosphate kinase that has been identified in human mitochondria. It is a component of the salvage pathway for nucleotide synthesis that may participate in terminal differentiation of monocytic cells. There are two distinct domains of CMPK2: the N-terminal domain with unknown function and the C-terminal domain with the kinase function, suggesting that CMPK2 may be a bifunctional protein with other biological functions in addition to its UMP-CMP kinase activity. CMPK2 may participate in dUTP and dCTP synthesis and is responsible for phosphorylation of dCMP and dUMP in mitochondria. CMPK2 is actively involved in macrophage activation and the inflammatory responseSynonyms: LOC129607, UMP-CMP kinase 2
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分子量
- 49 kDa
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基因ID
- 129607
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NCBI登录号
- NP_997198
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途径
- Nucleotide Phosphorylation, Cellular Response to Molecule of Bacterial Origin
抗原
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