CARD14 抗体 (C-Term)
Quick Overview for CARD14 抗体 (C-Term) (ABIN1449966)
抗原
See all CARD14 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
纯化方法
- Affinity Chromatography purified via peptide column
-
免疫原
- 14 amino acid synthetic peptide near the carboxy terminus of Human CARMA2
-
亚型
- IgG
-
-
anti-Caspase Recruitment Domain Family, Member 14 (CARD14) (AA 249-523) antibody
CARD14 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 14 (CARD14) (AA 1-434) antibodyCARD14 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 14 (CARD14) (Center) antibodyCARD14 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 14 (CARD14) (AA 905-1004) antibodyCARD14 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4B3 unconjugated
anti-Caspase Recruitment Domain Family, Member 14 (CARD14) (AA 200-500) antibodyCARD14 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- CARD14 (Caspase Recruitment Domain Family, Member 14 (CARD14))
-
别名
- CARD14 / CARMA2
-
背景
- CARMA proteins belong to the membrane-associated guan-ylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARMA1, CARMA2, and CARMA3 share high degrees of sequence and functional homology, but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types. As with CARMA1, the CARD domain of CARMA2 has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kB activation. When expressed in cells, this protein activated NF-kB and induced the phosphorylation of BCL10 Alternative splicing of CARMA2 results in isoforms that possess differential effects on NF-kB activation and endoplasmic reticulum stress-induced cell death.Synonyms: CARD-containing MAGUK protein 2, Caspase recruitment domain-containing protein 14
-
基因ID
- 79092
-
NCBI登录号
- NP_077015
抗原
-
