KPNA7 抗体 (N-Term)
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Quick Overview for KPNA7 抗体 (N-Term) (ABIN1449957)
抗原
See all KPNA7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 13 amino acid synthetic peptide near the amino terminus of Human KPNA7
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- KPNA7 (Karyopherin alpha 7 (Importin alpha 8) (KPNA7))
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别名
- KPNA7
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背景
- Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA7 is most closely related to KPNA2, but unlike KPNA2, KPNA7 primarily localizes to the nucleus. It has been suggested that KPNA7 may play a role in the transport of essential nuclear proteins required for early embryogenesis.Synonyms: Importin alpha 8, Importin subunit alpha-8, Karyopherin alpha 7, Karyopherin subunit alpha-7
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基因ID
- 402569
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NCBI登录号
- NP_001139187
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途径
- Protein targeting to Nucleus
抗原
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