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DELE1/KIAA0141 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects DELE1/KIAA0141 in WB, IF 和 EIA. It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN1449949
发货至: 中国
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Quick Overview for DELE1/KIAA0141 抗体 (N-Term) (ABIN1449949)

抗原

See all DELE1/KIAA0141 (DELE1) 抗体
DELE1/KIAA0141 (DELE1) (DAP3 Binding Cell Death Enhancer 1 (DELE1))

适用

  • 7
  • 1
  • 1
  • 1
人, 大鼠

宿主

  • 5
  • 2

克隆类型

  • 7
多克隆

标记

  • 7
This DELE1/KIAA0141 antibody is un-conjugated

应用范围

  • 7
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 4
    • 2
    • 1
    N-Term

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    18 amino acid synthetic peptide near the amino terminus of Human DELE

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    DELE1/KIAA0141 (DELE1) (DAP3 Binding Cell Death Enhancer 1 (DELE1))

    别名

    KIAA0141

    背景

    DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-alpha and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-alpha, anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors.

    基因ID

    9812

    NCBI登录号

    NP_055588
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