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PHOX2A 抗体 (C-Term)

This anti-PHOX2A antibody is a 兔 多克隆 antibody detecting PHOX2A in WB, IF, IHC (p) 和 EIA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN1449933
发货至: 中国

Quick Overview for PHOX2A 抗体 (C-Term) (ABIN1449933)

抗原

See all PHOX2A 抗体
PHOX2A (Paired-Like Homeobox 2a (PHOX2A))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This PHOX2A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    C-Term

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse, Rat.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    16 amino acid synthetic peptide near the carboxy terminus of Human PHOX2A

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    PHOX2A (Paired-Like Homeobox 2a (PHOX2A))

    别名

    PHOX2A

    背景

    PHOX2A and PHOX2B (Paired mesoderm homeobox protein) are closely related, paired-homeodomain transcription factors that function as determinants of the noradrenergic phenotype during embryogenesis. PHOX2 proteins are crucial for the regulation of endogenous hydroxylases in neural crest cells and promote sympathetic neuron generation. Human PHOX2B contains one DNA binding homeobox domain and is required for the differentiation of all central and nonperipheral noradrenergic centers in the brain. In contrast, PHOX2A controls only the differentiation of the main noradrenergic center of the brain. Regulation of PHOX2 may have therapeutic utility in aging or disorders involving degeneration of noradrenergic neurons.Synonyms: ARIX, ARIX1 homeodomain protein, Aristaless homeobox protein homolog, PMX2A, Paired mesoderm homeobox protein 2A, Paired-like homeobox 2A

    基因ID

    401

    NCBI登录号

    NP_005160
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