PHOX2A 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for PHOX2A 抗体 (C-Term) (ABIN1449933)
抗原
See all PHOX2A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
交叉反应 (详细)
- Species reactivity (tested):Human, Mouse, Rat.
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- 16 amino acid synthetic peptide near the carboxy terminus of Human PHOX2A
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- PHOX2A (Paired-Like Homeobox 2a (PHOX2A))
-
别名
- PHOX2A
-
背景
- PHOX2A and PHOX2B (Paired mesoderm homeobox protein) are closely related, paired-homeodomain transcription factors that function as determinants of the noradrenergic phenotype during embryogenesis. PHOX2 proteins are crucial for the regulation of endogenous hydroxylases in neural crest cells and promote sympathetic neuron generation. Human PHOX2B contains one DNA binding homeobox domain and is required for the differentiation of all central and nonperipheral noradrenergic centers in the brain. In contrast, PHOX2A controls only the differentiation of the main noradrenergic center of the brain. Regulation of PHOX2 may have therapeutic utility in aging or disorders involving degeneration of noradrenergic neurons.Synonyms: ARIX, ARIX1 homeodomain protein, Aristaless homeobox protein homolog, PMX2A, Paired mesoderm homeobox protein 2A, Paired-like homeobox 2A
-
基因ID
- 401
-
NCBI登录号
- NP_005160
抗原
-